T32 - NIH Training Grant on Metabolic Disease


Nutrition/Pharmacology -> Metabolic disease -> cardiovascular disease; cancer; diabetes; cognitive loss;

An NIH-funded T32 training grant entitled “Pharmacology and Nutritional Sciences: Multidisciplinary Approaches for Metabolic Disease” is housed in the Department of Pharmacology and Nutritional Sciences, Division of Nutritional Sciences. The training grant seeks to prepare biomedical scientists for academic careers in research focused on pharmacological and nutritional approaches to prevent and treat metabolic-based disorders. The training faculty come from eight different departments in four Colleges across the University of Kentucky campus. They have expertise in the four theme areas of the training grant: obesity/diabetes, cardiovascular disease, cancer, and neuroscience/aging.

Current pre-doctoral scholars supported by the training grant as of 9/1/2019:

Rupinder Kaur, Pharmaceutical Sciences
Project Description:  Pathways in the liver and intestine that maintain cholesterol elimination and homeostasis. 
Major Advisor:  Greg Graf, PhD, Department of Pharmaceutical Sciences 

Chi Peng, Pharmacology
Project Description:  Efficacy of the macrolide antibiotic, azithromycin (AZM), and derivatives in modulating the deleterious inflammatory responses after myocardial infarction, particularly in the setting of diabetes. 
Major Advisor:  Ahmed Abdel-Latif, MD PhD, Department of Internal Medicine

Gabriella Pugh, Microbiology, Immunology and Molecular Genetics
Project Description:  Mechanisms regulating the pro-inflammatory pathways that underlie the Th17 profile and metabolic status of individuals with obesity. 
Major Advisor:  Barbara Nikolajczyck, PhD, Department of Pharmacology and Nutritional Sciences

Stephanie Rock, Toxicology and Cancer Biology
Project Description: The role of intestinal hormone secretion on intestinal stem cell function in the context of high-fat diet.  
Major Advisor:  B. Mark Evers, MD, Department of Surgery

Lucille Yanckello, Nutritional Sciences
Project Description:  Caloric restriction and prebiotics as novel nutritional interventions in the treatment of age-related neurodegeneration and traumatic brain injury. 
Major Advisor: Ai-Ling Lin, PhD, Department of Pharmacology and Nutritional Sciences

Candidates for pre-doctoral positions must have a bachelor’s or master’s degree. Applicants must be U.S. citizens or permanent residents of the United States.  Interested individuals should contact the program directors:

Nancy R. Webb, PhD
Program Director

Department of Pharmacology and Nutritional Sciences
Director, Division of Nutritional Sciences
535 Wethington Health Sciences Building
Lexington, KY 40536-0200
Tel: (859) 218-1385
Email: nrwebb1@uky.edu
Profile: http://pharmns.med.uky.edu/users/nrwebb1

Lisa Cassis, PhD
Program Co-Director

Department of Pharmacology and Nutritional Sciences
Program Co-Director, Division of Nutritional Sciences
521b C.T. Wethington Building,
900 S Limestone St, Lexington, KY 40536-0200
Tel: (859)-323-4933 ext 81400
Email: lcassis@uky.edu
Profile: https://pharmns.med.uky.edu/users/lcassis