For University of Kentucky Vice President for Research Lisa Cassis the drive to conduct meaningful research is personal. “You don’t go into it for the money, you go into it because you want to help people,” Cassis said. The longtime UK professor chose to devote her career to cardiovascular research after watching her father battle heart disease for nearly 30 years. He suffered his first heart attack at age 51, went through three open heart surgeries, and was able to live until age 80 by managing his diet. However, Cassis says his lipid problems kept coming back no matter what he did. “I wanted to know why we aren’t able to help someone like... FULL STORY
Analia Loria, assistant professor of pharmacology and nutritional sciences at the University of Kentucky, will be a featured presenter at the First Physiology and Gender Conference organized by the American Physiological Society this week. At the conference, Loria will be discussing her research on the susceptibility of rodents to develop cardiovascular disease and metabolic syndrome in adulthood after being exposed to high-stress situations early in life. Loria utilizes animal models to study the effects in the cardiovascular system to mimic children that have been exposed to psychosocial stresses such as abuse, neglect, parental loss and other traumas. The stress, in... FULL STORY
Doctors commonly recommend patients increase their intake of calcium as a means of combating osteoporosis for aging bones. But calcium also plays an essential role in the neurological functioning of the brain, where it must be tightly regulated and not rise to excessive levels. A signaling molecule, calcium enables learning, cognition and the retention of memories. Calcium also facilitates communication among nerve cells and transports molecules to the many branches of the nerve cell. Building on scientific evidence implicating disturbed calcium regulation in brain aging accumulated through the past 30 years, a research team in the University of Kentucky... FULL STORY
Doctor of Philosophy: Junting Ai, China; Kate Townsend Creasy, Richmond, VA; Paulina Renee Davis, Temecula, CA; Leann Sara Fiore, Tulsa, OK; Sang Hee Lee, South Korea; Kristen Platt, Flemingsburg, KY; Robin Camille Shoemaker, Farmington, NM; Joel Christopher Thompson, Lexington, KY; Congqing Wu, Lexington, KY Master of Science: Maram Kalid Alhowaish, Lexington, KY; Reem Othman Basaqr, Saudi Arabia; Mariem Boughoula, Lexington, KY; Evan Cassity, Paris, KY; Cory Steven Eakins, Madisonville, KY; Corey Joseph Hawes, Louisville, KY; Marissa Mae Kruthaup, Morrow, OH; Murong Ma, China; Shreya Vikram Patel, India; Nicolle Putnam, Hartley, IA; Xinyu Qi, China; Chia-Hua Wu,... FULL STORY
The University of Kentucky’s fifth annual Barnstable Brown Obesity and Diabetes Research Day was held on May 20 at the Albert B. Chandler Hospital Pavilion A. Since 2011, the event has focused on current findings in obesity and diabetes research and features presentations by nationally prominent physician-scientists as well as the work of regional researchers and UK students, postdoctoral fellows and faculty chosen from abstract submissions. President Eli Capilouto opened the day with remarks about the importance of diabetes research at UK, given the prevalence of the disease in the region and the fact that diabetes is one of the leading causes of death and disability... FULL STORY
Two researchers from the Sanders-Brown Center on Aging have received a multi-million dollar grant renewal to unlock the mysteries of Alzheimer's disease (AD) and brain aging with the help of people with Down syndrome (DS). People with Down syndrome have a third copy of Chromosome 21, and that chromosome is the same one responsible for the production of a molecule called amyloid precursor protein. Since amyloid overproduction causes the brain plaques that are a cardinal feature of AD, virtually 100 percent of DS people have Alzheimer's pathology in their brain by the time they are 40, although many of them do not yet have the dementia that is the clinical... FULL STORY
"Drug Interactions in Breast Cancer" project has the potential to help scientists understand why the drug tamoxifen may not work as a therapy for breast cancer in some patients. Hollie Swanson, professor in the Department of Pharmacology and Nutritional Sciences, and Ok-Kyong Park-Sarge, associate professor in the Department of Physiology, worked with 10 STEMCats students on the project. The group focused on the question, "If breast cancer patients taking tamoxifen are also taking drugs to treat epilepsy or heart failure, would those drugs interfere with tamoxifen and inhibit their breast cancer treatment?" In addition to addressing a real-world issue through... FULL STORY
Dr. John Fowlkes took the helm as new director of the University of Kentucky's Barnstable Brown Diabetes and Obesity Center earlier this year with a vision to build upon the center's past work and develop a robust and comprehensive adult and pediatric center providing research, education and patient care for the thousands of Kentuckians diagnosed with diabetes. But the Texas native who has spent the last decade at the University of Arkansas Children's Hospital, has found himself in familiar territory. Fowlkes, who succeeds Dr. Philip Kern who served as the Center's inaugural director and who had been performing a dual role as director of the UK's Center for Clinical... FULL STORY
On Friday, February 6, 2015 the Department of Pharmacology and Nutritional Sciences hosted the University of Kentucky’s inaugural “Wear Red Day” symposium to raise awareness for cardiovascular research in women. The event was a part of the annual “National Wear Red Day” sponsored by the American Heart Association (AHA) that takes place on the first Friday of February. National Wear Red Day was initiated in 2003 in response to the alarming fact that 1 in 3 women die of heart disease and stroke each year, yet 80 percent of cardiac events can be prevented with education and lifestyle changes. Drs. Analia Loria and Frederique Yiannikouris from the Department of... FULL STORY
Registration is now available for the fifth annual Barnstable Brown Obesity... FULL STORY
Shuxia Wang, MD, Ph.D., has received NIH RO1 funding for a project titled "Thrombospondin1 in obesity associated inflammation and insulin resistance." The project will be supported by $1,204,651 grant for the period of August 2014 to May 2018. In addition, Dr. Wang recently received a competitive score for an R03 award to study interventions that may reduce acute kidney injury in the elderly. Dr. Wang joined the University of Kentucky faculty in 2005, and has served extensively in the areas of research, graduate training, and education. Dr. Wang has a productive extramurally funded research program focused on diabetic nephropathy.
Dr. Michael Kilgore, PhD, received recognition as a “Teacher Who Made a Difference” at the 16th Annual Teachers Who Made a Difference awards ceremony on April 26, 2014. More than 150 teachers’ names were put forward, including teachers from across the Commonwealth of Kentucky as well as teachers from Illinois, Indiana, Louisiana, New York, North Carolina, Tennessee and Ohio. The program, hosted by the University of Kentucky College of Education, was begun in 1998 to recognize educators who made a positive impact on the lives of their students. Congratulations Dr. Kilgore.